A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name PS1 siRNA
ncRNA Category siRNA
Disease name choroidal neovascularization (CNV)
Species Mus musculus
Tissues/Cell_line mouse neural retinas and RPE/choroid
Methods tube formation assay, Western blot, siRNA injection, immunohistochemistry, qRT-PCR
Expression pattern associated
Functional description SiRNA inhibition of γ-Secretase resulted in increased angiogenesis.
PubMed ID 22205609
Year 2012
Title γ-Secretase inhibition of murine choroidal neovascularization is associated with reduction of superoxide and proinflammatory cytokines.
Drug-related ncRNA NO

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