A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name PS1 siRNA
ncRNA Category siRNA
Disease name choroidal neovascularization (CNV)
Species Bos taurus
Tissues/Cell_line bovine retinal microvascular endothelial cells
Methods tube formation assay, Western blot, siRNA transfection, immunohistochemistry, qRT-PCR
Expression pattern associated
Functional description SiRNA inhibition of γ-Secretase resulted in increased angiogenesis.
PubMed ID 22205609
Year 2012
Title γ-Secretase inhibition of murine choroidal neovascularization is associated with reduction of superoxide and proinflammatory cytokines.
Drug-related ncRNA NO

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