|choroidal neovascularization (CNV)
|human RPE cell line ARPE-19; umbilical vein endothelial cell line EA hy926; human embryonic kidney cell line HEK293
|immunohistochemistry, transfection, Western blot, qRT-PCR, luciferase reporter assay
|NFκB activation inhibits miR-29s, which may contribute to angiogenesis by up-regulating the MMP-2 protein level in RPE cells.
|Roles of NFκB-miR-29s-MMP-2 circuitry in experimental choroidal neovascularization.
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