A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name VEGFR2 siRNA
ncRNA Category siRNA
Disease name choroidal neovascularization (CNV)
Species Mus musculus
Tissues/Cell_line RPE/choroid complex
Methods siRNA injection, fluorescein angiography, confocal microscopy, qRT-PCR
Expression pattern associated
Functional description Anti-VEGFA/VEGFR2 or non-specific siRNA can inhibit CNV and attenuate VEGF mRNA expression in a laser-induced mouse model of CNV.
PubMed ID 20599960
Year 2010
Title Inhibition of experimental choroidal neovascularization in mice by anti-VEGFA/VEGFR2 or non-specific siRNA.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.