|factor B siRNA
|choroidal neovascularization (CNV)
|RPE-choroid-scleral tissues, serum
|siRNA injection, immunohistochemistry, RT-PCR, Western blot
|Inhibition of the alternative pathway by factor B siRNA resulted in decreased levels of membrane attack complex and angiogenic factors-vascular endothelial growth factor and TGF-beta2.
|Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H.
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.