A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name T7 siRNA
ncRNA Category siRNA
Disease name choroidal neovascularization (CNV)
Species Homo sapiens
Tissues/Cell_line human primary RPE cells
Methods semi-qRT-PCR, immunofluorescence
Expression pattern associated
Functional description T7-siRNA can effectively and specifically suppress VEGF expression in hRPE cells and may be a new way to treat CNV.
PubMed ID 15820087
Year 2005
Title Inhibition of vascular endothelial growth factor gene expression by T7-siRNAs in cultured human retinal pigment epithelial cells.
Drug-related ncRNA NO

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