A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name hsa-miR-24
ncRNA Category miRNA
Disease name choroidal neovascularization (CNV)
Species Homo sapiens
Tissues/Cell_line human umbilical vein endothelial cells (HUVECs)
Methods transfection, qRT-PCR, Northern blot, Western blot, luciferase reporter assay
Expression pattern up-regulated
Functional description miR-24 has been shown to regulate apoptosis and inhibit cell proliferation. In the absence of miR-23 and miR-27, there is a compensatory up-regulation of miR-24 in our in vitro and in vivo knockdown assays. The potential role of miR-24 in angiogenesis awaits future studies.
PubMed ID 21536891
Year 2011
Title Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23~27~24 clusters.
Drug-related ncRNA NO

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