A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name mTOR shRNA
ncRNA Category shRNA
Disease name choroidal neovascularization (CNV)
Species Mus musculus
Tissues/Cell_line RPE-choroid complex, neural retinas
Methods shRNA knockdown, FFA, immunohistochemistry, RT-PCR
Expression pattern associated
Functional description Significantly fewer inflammatory cells and less extensive CNV were observed in the animals treated with rAAV-mTOR shRNA when compared with control- and rAAV-scrambled shRNA-treated groups.
PubMed ID 28918027
Year 2017
Title Adeno-Associated Viral Vector-Mediated mTOR Inhibition by Short Hairpin RNA Suppresses Laser-Induced Choroidal Neovascularization.
Drug-related ncRNA NA

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