A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name VEGF shRNA
ncRNA Category shRNA
Disease name choroidal neovascularization (CNV)
Species Mus musculus
Tissues/Cell_line muscle, eyes
Methods shRNA knockdown, PCR, histological analysis
Expression pattern associated
Functional description In the murine model of CNV, the sizes of the CNV were significantly reduced (up to 48%) following scAAV2/8-hU6-sh9 subretinal delivery.
PubMed ID 23080553
Year 2012
Title Reduction of choroidal neovascularization in mice by adeno-associated virus-delivered anti-vascular endothelial growth factor short hairpin RNA.
Drug-related ncRNA NA

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