ncRNA name | VEGF shRNA |
ncRNA Category | shRNA |
Disease name | choroidal neovascularization (CNV) |
Species | Mus musculus |
Tissues/Cell_line | mouse eyes |
Methods | shRNA knockdown, fluorescence microscopy, histology and lectin staining, fluorescein angiography |
Expression pattern | associated |
Functional description | shRNA targeting VEGF from adenovirus vectors allows potent attenuation of VEGF and prevents CNV. |
PubMed ID | 16877421 |
Year | 2006 |
Title | Inhibition of choroidal neovascularization by adenovirus-mediated delivery of short hairpin RNAs targeting VEGF as a potential therapy for AMD. |
Drug-related ncRNA | NA |
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