A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name Ets1 siRNA
ncRNA Category siRNA
Disease name choroidal neovascularization (CNV)
Species Mus musculus
Tissues/Cell_line choroid-RPE-retina complex
Methods Western blot, immunofluorescence, siRNA injection, FFA, immunofluorescence staining
Expression pattern associated
Functional description Ets1 siRNA intravitreal injection ameliorated the leakage and area of CNV, as well as inhibiting the dysfunction of retinal pigment epithelium (RPE) cells and the activation of macrophages/microglia.
PubMed ID 30834976
Year 2019
Title Intravitreal Ets1 siRNA alleviates choroidal neovascularization in a mouse model of age-related macular degeneration.
Drug-related ncRNA NO

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