A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name TFAF6 siRNA
ncRNA Category siRNA
Disease name choroidal neovascularization (CNV)
Species Mus musculus
Tissues/Cell_line RPE-choroid-sclera complexes and retinas
Methods Western blot, immunohistochemistry, siRNA injection, FFA, ICGA, immunofluorescence
Expression pattern associated
Functional description TFAF6 inhibition reduces CNV formation via down-regulating expression of HIF-1α and VEGF and activation of macrophages and microglia.
PubMed ID 30103950
Year 2018
Title Inhibition of TRAF6 alleviates choroidal neovascularization in vivo.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.