A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of cataract
ncRNA name hsa-miR-34a
ncRNA Category miRNA
Disease name cataract
Species Homo sapiens
Tissues/Cell_line human lens epithelial cell line HLE-B3
Methods transfection, qRT-PCR, Western blot
Expression pattern up-regulated
Functional description miR-34a promotes the apoptosis of HLE-B3 cells by down-regulating Bcl-2 and SIRT1.
PubMed ID 27990356
Year 2016
Title MicroRNA-34a promoting apoptosis of human lens epithelial cells through down-regulation of B-cell lymphoma-2 and silent information regulator.
Drug-related ncRNA NO

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