A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of cataract
ncRNA name FoxO3A siRNA
ncRNA Category siRNA
Disease name cataract
Species Homo sapiens
Tissues/Cell_line primary human lens epithelial cells (LECs)
Methods flow cytometry, qPCR, Western blot, siRNA transfection
Expression pattern associated
Functional description SiRNA inhibition of FoxO1A, FoxO3A, and FoxO4 not only led to loss of the anti-apoptotic effects of RES in stressed cells but actually exhibited a mild pro-apoptotic effect.
PubMed ID 21345980
Year 2011
Title Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity.
Drug-related ncRNA NO

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