A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of cataract
ncRNA name hsa-miR-184
ncRNA Category miRNA
Disease name cataract
Species Homo sapiens
Tissues/Cell_line NA
Methods DNA sequencing
Expression pattern associated
Functional description In this study we report a five-generation family originating in Galicia, Spain with early onset cataracts and variable corneal abnormalities which include non-ectatic corneal thinning and severe early-onset keratoconus. We identified a heterozygous c.57 C > T mutation in miR-184 in the proband and two additional affected relatives on the maternal side.
PubMed ID 24138095
Year 2015
Title C.57 C > T Mutation in MIR 184 is Responsible for Congenital Cataracts and Corneal Abnormalities in a Five-generation Family from Galicia, Spain.
Drug-related ncRNA NO

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