A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of autoimmune uveitis
ncRNA name hsa-miR-223-3p
ncRNA Category miRNA
Disease name autoimmune uveitis
Species Homo sapiens
Tissues/Cell_line serum
Methods TaqMan OpenArray, qRT-PCR, flow cytometry
Expression pattern up-regulated
Functional description miR-223-3p is upregulated in animal models of uveitis and is able to drive inflammation via T cells and myeloid dendritic cells, two cell types that are implicated in the biology of uveitis.miR-223-3p has been suggested as a good candidate for miRNA targeting in the treatment of inflammatory diseases such as NIU.
PubMed ID 29435587
Year 2018
Title A Disease-Associated MicroRNA Cluster Links Inflammatory Pathways and an Altered Composition of Leukocyte Subsets to Noninfectious Uveitis.
Drug-related ncRNA NO

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