A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of autoimmune uveitis
ncRNA name hsa-miR-140-5p
ncRNA Category miRNA
Disease name autoimmune uveitis
Species Homo sapiens
Tissues/Cell_line serum
Methods TaqMan OpenArray, qRT-PCR, flow cytometry
Expression pattern up-regulated
Functional description miR-140-5p, which had the highest discriminative power between uveitis patients and controls, is aberrantly expressed and implicated in pathogenic T-cell function in multiple sclerosis, a disease linked to IU.we also noted associated pathways relevant for ocular biology, including VEGF signaling, photoreceptor development, and retina homeostasis.
PubMed ID 29435587
Year 2018
Title A Disease-Associated MicroRNA Cluster Links Inflammatory Pathways and an Altered Composition of Leukocyte Subsets to Noninfectious Uveitis.
Drug-related ncRNA NO

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