A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of autoimmune uveitis
ncRNA name rno-miR-17-5p
ncRNA Category miRNA
Disease name autoimmune uveitis
Species Rattus norvegicus
Tissues/Cell_line peripheral blood lymphocytes
Methods microarray, qRT-PCR
Expression pattern up-regulated
Functional description The results indicated that 36 miRNAs were upregulated and 31 miRNAs were downregulated in EAU rats versus normal samples. Real-time quantitative PCR substantiated a high degree of confidence for the differentially expressed miRNAs, and miRNA analyses showed the differentially expressed miRNA targets were involved not only in the multicellular organismal process and developmental process, but also in T cell receptor signaling pathway, B cell receptor signaling pathway and so on.
PubMed ID 26153870
Year 2015
Title Characterization of microRNA expression profiling in peripheral blood lymphocytes in rats with experimental autoimmune uveitis.
Drug-related ncRNA NO

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