A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related cataract
ncRNA name hsa-miR-34b-5p
ncRNA Category miRNA
Disease name age-related cataract
Species Homo sapiens
Tissues/Cell_line lens epithelium; human lens epithelial cell line HLE-B3
Methods microarray, qRT-PCR
Expression pattern up-regulated
Functional description According to the miRNAs’ fold change and expression level, five up-regulated miRNAs and two down-regulated miRNAs were chosen for microarray validation by RT-PCR. The result of the PCR analysis confirmed the differentially expressed miRNAs selected by microarray.
PubMed ID 29653565
Year 2018
Title Identification of H2O2 induced oxidative stress associated microRNAs in HLE-B3 cells and their clinical relevance to the progression of age-related nuclear cataract.
Drug-related ncRNA NO

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