A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related cataract
ncRNA name hsa-miR-204-5p
ncRNA Category miRNA
Disease name age-related cataract
Species Homo sapiens
Tissues/Cell_line epithelium-capsule of lens
Methods microarray
Expression pattern down-regulated
Functional description Four down-regulated miRNAs were found to target 3' UTR of pro-oxidative genes and could also bind to the TATA-box regions of anti-oxidative genes (with the exception of has-miR-204-3p).
PubMed ID 28806956
Year 2017
Title MiRNAs regulate oxidative stress related genes via binding to the 3' UTR and TATA-box regions: a new hypothesis for cataract pathogenesis.
Drug-related ncRNA NO

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