| ncRNA name | SP siRNA |
| ncRNA Category | siRNA |
| Disease name | acanthamoeba keratitis |
| Species | Rattus norvegicus |
| Tissues/Cell_line | corneas |
| Methods | siRNA transfection, histological analysis |
| Expression pattern | associated |
| Functional description | A murine model of ocular keratitis was treated with siGP + siSP-loaded liposomes, as well as their respective controls, and combined treatment of liposomes and chlorhexidine. After 15 days of eight daily administrations, the liposomal complex combined with chlorhexidine was the only treatment able to reverse the more severe lesions associated with keratitis. |
| PubMed ID | 30384269 |
| Year | 2019 |
| Title | Box Behnken design of siRNA-loaded liposomes for the treatment of a murine model of ocular keratitis caused by Acanthamoeba. |
| Drug-related ncRNA | NO |
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