|Pseudomonas aeruginosa keratitis
|siRNA injection, qPCR, cytokines assay, Western blot
|EMMPRIN promotes host resistance against pseudomonas aeruginosa infection via MAPK signaling pathway. Silence of EMMPRIN Enhanced the Production of pro-inflammatory cytokines in PA keratitis. Silence of EMMPRIN significantly up-regulated Th1-type cytokines IFN-γ, IL-12, and IL-18, but down-regulated Th2-type cytokines IL-4, IL-5, and IL-10.
|Extracellular matrix metalloproteinase inducer enhances host resistance against pseudomonas aeruginosa infection through MAPK signaling pathway.
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