|Pseudomonas aeruginosa keratitis
|siRNA injection, qRT-PCR, immunofluorescent staining, ELISA
|Inhibition of HIF-1α converts a normally resistant disease response to susceptible (corneal thinning and perforation) after induction of bacterial keratitis.
|HIF-1α is essential for effective PMN bacterial killing, antimicrobial peptide production and apoptosis in Pseudomonas aeruginosa keratitis.
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