ncRNA name | siTestican-1 |
ncRNA Category | siRNA |
Disease name | Pseudomonas aeruginosa keratitis |
Species | Mus musculus |
Tissues/Cell_line | corneas |
Methods | siRNA injection, immunostaining, qRT-PCR, ELISA, zymography, Western blot |
Expression pattern | associated |
Functional description | After rhTestican-1 treatment in B6 mice, overall disease response was significantly improved, whereas siRNA treatment of BALB/c mice converted the normally resistant response to susceptible. |
PubMed ID | 21613368 |
Year | 2011 |
Title | Testican-1 promotes resistance against Pseudomonas aeruginosa-induced keratitis through regulation of MMP-2 expression and activation. |
Drug-related ncRNA | NO |
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