A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of Pseudomonas aeruginosa keratitis
ncRNA name siTestican-1
ncRNA Category siRNA
Disease name Pseudomonas aeruginosa keratitis
Species Mus musculus
Tissues/Cell_line corneas
Methods siRNA injection, immunostaining, qRT-PCR, ELISA, zymography, Western blot
Expression pattern associated
Functional description After rhTestican-1 treatment in B6 mice, overall disease response was significantly improved, whereas siRNA treatment of BALB/c mice converted the normally resistant response to susceptible.
PubMed ID 21613368
Year 2011
Title Testican-1 promotes resistance against Pseudomonas aeruginosa-induced keratitis through regulation of MMP-2 expression and activation.
Drug-related ncRNA NO

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