ncRNA name | TSLPR siRNA |
ncRNA Category | siRNA |
Disease name | Pseudomonas aeruginosa keratitis |
Species | Mus musculus |
Tissues/Cell_line | corneas |
Methods | siRNA injection, ELISA, qPCR, Western blot |
Expression pattern | associated |
Functional description | Targeting TSLP or TSLPR with neutralizing antibodies or TSLPR with siRNA resulted in more severe keratitis, attributable to an increase in bacterial burden and PMN infiltration. |
PubMed ID | 30128494 |
Year | 2018 |
Title | TSLP Protects Corneas From Pseudomonas aeruginosa Infection by Regulating Dendritic Cells and IL-23-IL-17 Pathway. |
Drug-related ncRNA | NO |
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